
A 16-Year-Old Girl With Bilateral Visual Loss and Left Hemiparesis Following an Immunization Against Human Papilloma Virus
Francis J. DiMario, Jr, Mirna Hajjar and Thomas Ciesielski J Child Neurol 2010; 25; 321 DOI: 10.1177/0883073809349322 ONE CLICK EXTRACTS
We report the course of a 16-year-old girl who presented with near complete visual loss associated with chiasmal neuritis and a biopsy proven tumefactive demyelinating lesion on magnetic resonance imaging (MRI) in association with a recent immunization against human papilloma virus.
She had received her second vaccination against human papilloma virus 10 days prior to her presentation. There was no family history of demyelinating disease, collagen-vascular disease, or rheumatological disorders.
In the context of prior vaccination in a 16-year-old girl, acute demyelinating encephalomyelitis is likely to explain the multifocal deficits.
Larger epidemiologic studies will be needed to confirm a role of the human papilloma virus immunization and demyelinating disease.
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