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News Archives 4221-4240
Number Title Post Date
4221 The FBI's Anthrax Letters Investigation: Points To Consider 02/12/2010 14:21:21
4222 Legal Aid - UK ConDem Government Tries To Close Citizens Advice Bureaus 02/12/2010 14:24:39
4223 More UK MP Piggies Exploiting Taxpayer In Second Homes Scandal 02/12/2010 14:27:06
4224 UK MP Piggies Squealing, Still Trying To Avoid Justice 02/12/2010 14:29:21
4225 WikiLeaks' Julian Assange & The Swedish 'Justice System' Laughing Stock 02/12/2010 14:32:15
4226 WikiLeaks Reveals Governments Caught Up In A Mendacity Of Lies 02/12/2010 14:37:11
4227 Why Psychotherapies Never Get Better 03/12/2010 12:23:21
4228 London Killer Biolab Inquiry Announced 03/12/2010 12:26:02
4229 Mum Worries About Son's Health After Double Dose Swine Flu Vaccine 03/12/2010 12:27:35
4230 Dick Cheney Charged In $180M Bribery Case, Interpol Arrest Warrant Issued 03/12/2010 12:29:17
4231 Daniel Ellsberg Says Boycott Amazon For Cowardice 03/12/2010 12:31:11
4232 New Pneumococcal Vaccine Is Killing Babies - American Academy Of Pediatrics 03/12/2010 12:32:56
4233 WikiLeaks Cables: Live Q&A With Julian Assange At 1:00pm UK Time Today! 03/12/2010 12:35:22
4234 Ex MP David Chaytor Pleads Guilty To Expenses Fraud 06/12/2010 14:34:35
4235 RiME Questions ME/CFS Apostate Countess Of Mar 06/12/2010 14:40:27
4236 Red Cross Bars Chronic Fatigue Syndrome (ME/CFS) Patients From Donating Blood 06/12/2010 14:43:48
4237 Autism & ME/CFS - A Modern Day Munchausen Syndrome By Proxy Scandal 06/12/2010 14:50:22
4238 Mother's Plea To Help Fight Sanofi-Aventis Epilim Drug Birth Defects Class Action 06/12/2010 14:56:08
4239 CDC Birth Defects Study Implicates Popular Fertility Drug, Sanofi-Aventis Clomid 06/12/2010 14:58:57
4240 Influenza Vaccine Trials - Evidence Of Widespread Manipulation Of Conclusions 06/12/2010 15:01:30

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Influenza Vaccine Trials - Evidence Of Widespread Manipulation Of Conclusions
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Dr Meryl Nass, MD

Sunday, December 5, 2010

Influenza vaccine clinical trials: reliable evidence is thin, but there is evidence of widespread manipulation of conclusions/ Cochrane

A 2010 update to Cochrane's 2007 metaanalysis of the published clinical trial literature on influenza vaccinations found not a lot to recommend the vaccines.  Cochrane pointed out, "Healthy adults are presently targeted mainly in North America."  The implication is that Europe, where most reviewers reside, is too smart to push mass flu shots on its healthy population.

In the relatively uncommon circumstance of vaccine matching the viral circulating strain and high circulation, 4% of unvaccinated people versus 1% of vaccinated people developed influenza symptoms (risk difference (RD) 3%, 95% confidence interval (CI) 2% to 5%)...  Vaccination had a modest effect on time off work and had no effect on hospital admissions or complication rates. Inactivated vaccines caused local harms and an estimated 1.6 additional cases of Guillain-Barré Syndrome per million vaccinations. The harms evidence base is limited.
CONCLUSIONS: Influenza vaccines have a modest effect in reducing influenza symptoms and working days lost. There is no evidence that they affect complications, such as pneumonia, or transmission.WARNING: This review includes 15 out of 36 trials funded by industry (four had no funding declaration). An earlier systematic review of 274 influenza vaccine studies published up to 2007 found industry funded studies were published in more prestigious journals and cited more than other studies independently from methodological quality and size. Studies funded from public sources were significantly less likely to report conclusions favorable to the vaccines. The review showed that reliable evidence on influenza vaccines is thin but there is evidence of widespread manipulation of conclusions and spurious notoriety of the studies. The content and conclusions of this review should be interpreted in light of this finding.

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Related Links:
* Influenza Vaccines: Poor Evidence for Effectiveness in Elderly
Press Release, Science Daily
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